In our days diabetes becomes a big problem even when patients are given insulin and stay on strict diets. In many countries it is a considered to be an occasion of social concern, so developing new drugs and therapies effective in diabetes therapy is a crucial target. Under these circumstances, the new discovery of a scientific team at John Hopkins institute regarding a possible new approach to fight diabetes is very important and welcomed by medical world. The subject of investigations was a protein called GCN5. Recent studies revealed that this protein is very important for keeping under control a domino-like cascade of molecular facts that generate free discharge of sugar from liver cells directly into the bloodstream. Critical conditions like obesity and diabetes are a consequences of the body inability to properly control the blood sugar levels. It is a fact that patients having type 1 or type 2 diabetes have high blood sugar levels and this condition can lead to severe complications like kidney failure, blindness and nerve damage. The new approach of this scientific team is to lower blood sugar levels by controlling the release of sugar by liver cells. Introducing the protein GCN5 in diabetes patients' liver, it can in fact induce a decrease of blood glucose levels. The conclusion of the study was that changing GCN5 status in sufferers liver is sufficient to control the sugar balance |
